Evaluation of Photoprotective Potential in Flowers of Osbeckia octandra (L.) DC. for the Development of Herbal Sunscreen Formulations
exposure to ultraviolet (UV) radiation of the solar spectrum is often linked with
the onset of conditions like inflammation, photoaging, immunosuppression,
hyperpigmentation, and photocarcinogenesis. Although synthetic sunscreens have emerged
as protectants against this harmful UV radiation, there is an increasing demand
for sunscreens of herbal origin, which are believed to have low side-effect
profiles in comparison to their synthetic counterparts. In order to cater for this
need, the present study aimed at developing herbal sunscreen formulations from
flowers of Osbeckia octandra DC, a purple-coloured wildflower widely
distributed across different geographical regions in Sri Lanka.
Methodology: The UV
filtering potency and subsequently, the sun protection factor (SPF) in the
methanolic extract of O. octandra was initially determined. Thereafter
this extract was incorporated into the aqueous cream base at 25%, 50%,
and 75% and the SPF values and photostability of the prepared formulations were
initial SPF value of the crude extract (39.91) had hardly changed even after
incorporating it at 75% into the aqueous cream base. This 75% formulation surpassed
the other two formulations and the commercial sunscreen (positive control) in
terms of the higher SPF and broader spectrum
of UV absorption. Its SPF value altered
only slightly during the storage for 21 days in light or dark conditions and was
Conclusion: Our preliminary observations demonstrated the appropriateness of O.
octandra for the formulation of herbal sunscreens at the commercial stage.